Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders’ meeting held in Entebbe, Uganda.

Name	World Continuing Education Alliance
Activity Title	Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders’ meeting held in Entebbe, Uganda.
Details	Effective vaccines have proven extremely useful in the prevention of infectious diseases, but are still lacking for major poverty-related and neglected infections, including helminth infections. The conventional approach to vaccine development, testing efficacy in human subjects in large Phase III trials after safety and immunogenicity are confirmed through smaller Phase I and II trials, is lengthy and extremely costly. An alternative approach, to identify the most promising candidate vaccines through controlled human infection (CHI) models (typically referred to as Phase IIa), is gaining acceptance and application for infections including malaria, typhoid and others: to date about 22,000 volunteers have been infected, safely, with 23 different pathogens. Schistosomiasis is a major parasitic infectious disease, considered second only to malaria as a parasitic cause of morbidity and mortality. As a first step towards establishing the CHI-S in an endemic setting, we held a stakeholders m...
Competence	Public Health
Start Date	<span class="not-set">(not set)</span>
End Date	<span class="not-set">(not set)</span>
Event Time	09:30 AM
Location	World Continuing Education Alliance eLearning System
Cost (UGX)	0
CPD Points	1