Genetic analysis of measles virus nucleocapsid gene identifies measles virus isolate of close similarity to Clade A viruses from Nigeria

NameWorld Continuing Education Alliance
Activity TitleGenetic analysis of measles virus nucleocapsid gene identifies measles virus isolate of close similarity to Clade A viruses from Nigeria
DetailsMeasles is an acute viral illness characterised by a prodromal illness of fever, coryza, cough, conjunctivitis and presence of Koplik spots followed by the appearance of a generalised maculopapular rash. The illness is either mild or severe depending on the immune and nutritional status of the infected person. It is caused by measles virus (MV), which is a negative sense single stranded RNA virus of the family Paramyxoviridae, genus Morbillivirus. The 450 nucleotides that code for the COOH-terminus of the N protein is the single most variable part of the measles genome and analysis of this part of MV isolates or clinical specimens has helped to classify measles into eight clades (Clades A-H) and 23 genotypes. Previous reports on circulating measles strains from Nigeria have indicated the circulation of only genotypes B3 cluster 1 and 2. However, due to the absence of integrated molecular surveillance in measles’ elimination programs, there has been only a few sequence data of Nigerian ...
CompetencePublic Health
Start Date<span class="not-set">(not set)</span>
End Date<span class="not-set">(not set)</span>
Event Time12:15 PM
LocationWorld Continuing Education Alliance eLearning System
Cost (UGX)0
CPD Points1