Case Report: Stevens-Johnson syndrome following a single double dosing of nevirapine-containing regimen once in an HIV-infected woman on long-term antiretroviral therapy.

Name	World Continuing Education Alliance
Activity Title	Case Report: Stevens-Johnson syndrome following a single double dosing of nevirapine-containing regimen once in an HIV-infected woman on long-term antiretroviral therapy.
Details	Nevirapine (NVP)-based antiretroviral regimens have been used widely in developing countries because of its affordability, availability and efficacy. In larger series, the incubation period before developing features of SJS ranges from 10–240 days with a median duration of around 12 daysn Objectives Course Objective A 31-year old HIV-infected African woman on nevirapine, tenofovir and lamivudine for more than 4 years presented with an 8-day history of symptoms and signs of Stevens-Johnson syndrome. She was on no other medication. Her viral load was undetectable and she had maintained a CD4 count of between 356 and 387cells/mm. Her ARVs were stopped and she fully re-epithelialized with the exception of the lips, over the following 10 days. She was started on a daily single tablet of Odimune® (a fixed drug combination antiretroviral containing tenofovir, emtricitabine and efavirenz)..
Competence	Public Health
Start Date	<span class="not-set">(not set)</span>
End Date	<span class="not-set">(not set)</span>
Event Time	10:45 PM
Location	World Continuing Education Alliance eLearning System
Cost (UGX)	0
CPD Points	1