IL-15 enhances cross-reactive antibody recall responses to seasonal H3 influenza viruses in vitro

Name	World Continuing Education Alliance
Activity Title	IL-15 enhances cross-reactive antibody recall responses to seasonal H3 influenza viruses in vitro
Details	Worldwide, annual influenza epidemics are estimated to result in about 3 to 5 million cases of severe illness, and about 250,000 to 500,000 deaths. Since jumping species to humans in 1968, H3N2 swine flu viruses have been responsible for several seasonal pandemics, resulting in both prolonged duration of the influenza season and greater disease severity. In contrast to the variable HA head domain, epitopes within the HA stalk domain are highly conserved and have become a main target for development of novel treatments using either antibody-based vaccine design or passive immunotherapy. Several human monoclonal antibodies that target highly conserved epitopes on the stalk region of influenza HA display broad reactivity with group 1 and/or group 2 viruses and protect against lethal challenge with influenza viruses. Several strategies have been employed in an attempt to improve broadly cross-reactive IgG production by application of a non-specific stimulus, the most common of which is the...
Competence	Public Health
Start Date	<span class="not-set">(not set)</span>
End Date	<span class="not-set">(not set)</span>
Event Time	11:30 AM
Location	World Continuing Education Alliance eLearning System
Cost (UGX)	0
CPD Points	1