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- Characterization of potential drug targeting folate transporter proteins from Eukaryotic Pathogens
Characterization of potential drug targeting folate transporter proteins from Eukaryotic Pathogens
| Name | World Continuing Education Alliance |
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| Activity Title | Characterization of potential drug targeting folate transporter proteins from Eukaryotic Pathogens |
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| Details | A heterogeneous diversity of eukaryotic pathogens is responsible for the most economically important diseases of humans and animals. A metabolic pathway that has been exploited considerably for the development of drugs is the folate biosynthetic pathway. In addition to the folate biosynthesis pathway, proteins that mediate transport of useful nutrients such as folic acid have been identified as important chemotherapeutic drug targets. Proteins that mediate transportation of folates have been well studied in a few parasites such as. Therefore, in an attempt to identify and characterize targets for novel therapeutics, we report herein an extensive search of folate transporters from pathogen genomes. In addition, we investigated the evolutionary relationship of these transporters in a bid to determine similarities and differences that make them attractive drug targets. The knowledge provided may assist in the design of new antifolates for protozoan parasites. |
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| Competence | Internal Medicine |
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| Start Date | <span class="not-set">(not set)</span> |
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| End Date | <span class="not-set">(not set)</span> |
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| Event Time | 11:15 PM |
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| Location | World Continuing Education Alliance eLearning System |
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| Cost (UGX) | 0 |
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| CPD Points | 1 |
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