Association between CD4 T cell counts and the immune status among adult critically ill HIV-negative patients in intensive care units in Uganda

Name	World Continuing Education Alliance
Activity Title	Association between CD4 T cell counts and the immune status among adult critically ill HIV-negative patients in intensive care units in Uganda
Details	Cluster of differentiation 4 (CD4) is a glycoprotein found on the surface of immune cells such as T helper cells and macrophages. Critical care has become an important area of the health sciences, leading to development of scoring systems to guide clinicians in estimating patients’ prognoses, and in particular the risk of mortality. The most frequently used scoring system is the Acute Physiology Age and Chronic Health Evaluation II (APACHE II). Low CD4 T cell counts were associated with mortality among HIV patients admitted to African ICU. No such study had been conducted in Uganda before; hence, no available policies regarding use of CD4 T cell counts among critically ill HIV-negative patients from the Ugandan Ministry of Health. Objectives Course Objective : Cluster of differentiation 4 (CD4) T cells play a central role in regulation of adaptive T cell-mediated immune responses. Low CD4 T cell counts are not routinely reported as a marker of immune deficiency among HIV-negative individuals, as is the norm among their HIV positive counterparts. Despite evidence of mortality rates as high as 40% among Ugandan critically ill HIV-negative patients, the use of CD4 T cell counts as a measure of the immune status has never been explored among this population. This study assessed the immune status of adult critically ill HIV-negative patients admitted to Ugandan intensive care units (ICUs) using CD4 T cell count as a surrogate marker.. A multicentre prospective cohort was conducted between 1.
Competence	Public Health
Start Date	<span class="not-set">(not set)</span>
End Date	<span class="not-set">(not set)</span>
Event Time	06:15 PM
Location	World Continuing Education Alliance eLearning System
Cost (UGX)	0
CPD Points	1